Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure

To investigate tumor resistance to T cell lysis, a resistant variant was selected after specific cytolytic T lymphocytes (CTL) selection pressure. Although the resistant variant triggered perforin and granzyme B transcription in specific CTLs, as well as their degranulation, it exhibited a dramatic...

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Detalhes bibliográficos
Main Authors: Abouzahr, Soraya, Bismuth, Georges, Gaudin, Catherine, Caroll, Oliver, Van Endert, Peter, Jalil, Abdelali, Dausset, Jean, Vergnon, Isabelle, Richon, Catherine, Kauffmann, Audrey, Galon, Jérôme, Raposo, Graca, Mami-Chouaib, Fathia, Chouaib, Salem
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360579/
https://ncbi.nlm.nih.gov/pubmed/16432193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510454103
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