Upstream AUGs in embryonic proinsulin mRNA control its low translation level

Proinsulin is expressed prior to development of the pancreas and promotes cell survival. Here we study the mechanism affecting the translation efficiency of a specific embryonic proinsulin mRNA. This transcript shares the coding region with the pancreatic form, but presents a 32 nt extended leader r...

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Bibliografski detalji
Glavni autori: Hernández-Sánchez, Catalina, Mansilla, Alicia, de la Rosa, Enrique J., Pollerberg, G.Elisabeth, Martínez-Salas, Encarna, de Pablo, Flora
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2003
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC213770/
https://ncbi.nlm.nih.gov/pubmed/14532130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg515
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