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Upstream AUGs in embryonic proinsulin mRNA control its low translation level
Proinsulin is expressed prior to development of the pancreas and promotes cell survival. Here we study the mechanism affecting the translation efficiency of a specific embryonic proinsulin mRNA. This transcript shares the coding region with the pancreatic form, but presents a 32 nt extended leader r...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC213770/ https://ncbi.nlm.nih.gov/pubmed/14532130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg515 |
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