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Differential utilization of upstream AUGs in the β-secretase mRNA suggests that a shunting mechanism regulates translation
β-Secretase [also known as the β-site amyloid precursor protein-cleaving enzyme 1 (BACE1)] is an enzyme involved in the production of Aβ-amyloid plaques in the brains of patients with Alzheimer's disease. The enhanced production of this enzyme occurs without corresponding changes in BACE1 mRNA...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365699/ https://ncbi.nlm.nih.gov/pubmed/14981268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308576101 |
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