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Developmental regulation of a proinsulin messenger RNA generated by intron retention

Proinsulin gene expression regulation and function during early embryonic development differ remarkably from those found in postnatal organisms. The embryonic proinsulin protein content decreased from gastrulation to neurulation in contrast with the overall proinsulin messenger RNA increase. This is...

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Autors principals: Mansilla, Alicia, López-Sánchez, Carmen, de la Rosa, Enrique J, García-Martínez, Virginio, Martínez-Salas, Encarna, de Pablo, Flora, Hernández-Sánchez, Catalina
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369204/
https://ncbi.nlm.nih.gov/pubmed/16179943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400539
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