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T cell-independent type I antibody response against B cell epitopes expressed repetitively on recombinant virus particles

Recombinant viral or virus-like particles offer new tools for vaccine development. This study investigated hepatitis B core antigen (HBcAg) capsids and RNA phage Qβ coats as carriers of a foreign epitope to induce antibody responses in mice. HBcAg capsids were shown to induce T cell-independent (TI)...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Fehr, Thomas, Skrastina, Dace, Pumpens, Paul, Zinkernagel, Rolf M.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1998
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC21363/
https://ncbi.nlm.nih.gov/pubmed/9689105
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