Construction and Immunological Evaluation of Multivalent Hepatitis B Virus (HBV) Core Virus-Like Particles Carrying HBV and HCV Epitopes

A multivalent vaccine candidate against hepatitis B virus (HBV) and hepatitis C virus (HCV) infections was constructed on the basis of HBV core (HBc) virus-like particles (VLPs) as carriers. Chimeric VLPs that carried a virus-neutralizing HBV pre-S1 epitope corresponding to amino acids (aa) 20 to 47...

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Detalhes bibliográficos
Main Authors: Sominskaya, Irina, Skrastina, Dace, Dislers, Andris, Vasiljev, Denis, Mihailova, Marija, Ose, Velta, Dreilina, Dzidra, Pumpens, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884416/
https://ncbi.nlm.nih.gov/pubmed/20410327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00468-09
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