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A VLP Library of C-Terminally Truncated Hepatitis B Core Proteins: Correlation of RNA Encapsidation with a Th1/Th2 Switch in the Immune Responses of Mice

An efficient pBR327- and Ptrp-based E. coli expression system was used to generate a large-scale library of virus like particles (VLP) formed by recombinant hepatitis B virus (HBV) core (HBc) protein derivatives. To construct the library, the gene of HBc protein of the genotype D/subtype ayw2 virus...

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Библиографические подробности
Главные авторы: Sominskaya, Irina, Skrastina, Dace, Petrovskis, Ivars, Dishlers, Andris, Berza, Ieva, Mihailova, Maria, Jansons, Juris, Akopjana, Inara, Stahovska, Irina, Dreilina, Dzidra, Ose, Velta, Pumpens, Paul
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781094/
https://ncbi.nlm.nih.gov/pubmed/24086668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075938
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