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Apparent Directional Scanning for DNA Repair
Recently it was observed that the DNA repair protein human O(6)-alkylguanine-DNA alkyltransferase repairs lesions at the 5′ ends of 70-nucleotide single-stranded DNA roughly threefold more frequently than lesions at the 3′ ends. Here, we introduce a coarse-grained model to show how a local asymmetry...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2134852/ https://ncbi.nlm.nih.gov/pubmed/17827238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.110619 |
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