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Enhancement of Diffusion-Controlled Reaction Rates by Surface-Induced Orientational Restriction

We explore the means by which immobilization of a substrate on a surface can increase the rate of a diffusion-controlled enzymatic reaction. A quasichemical approach is developed and compared with Brownian dynamics simulations. We use these methods to show that restricting only the orientation of th...

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Detalhes bibliográficos
Main Authors: Nag, Ambarish, Dinner, Aaron R.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367114/
https://ncbi.nlm.nih.gov/pubmed/16299070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072785
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