Intrapatient Dose Escalation of Anti–CTLA-4 Antibody in Patients With Metastatic Melanoma

We previously reported our experience in treating 56 patients with metastatic melanoma using a human anti-cytotoxic T-lymphocyte antigen 4 (CTLA-4) antibody. Durable tumor regressions were seen that correlated with the induction of autoimmune toxicities. In this study, we treated 46 additional patie...

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Bibliografiset tiedot
Päätekijät: Maker, Ajay V., Yang, James C., Sherry, Richard M., Topalian, Suzanne L., Kammula, Udai S., Royal, Richard E., Hughes, Marybeth, Yellin, Michael J., Haworth, Leah R., Levy, Catherine, Allen, Tamika, Mavroukakis, Sharon A., Attia, Peter, Rosenberg, Steven A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134804/
https://ncbi.nlm.nih.gov/pubmed/16799341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.cji.0000208259.73167.58
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