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Universal patterns of purifying selection at noncoding positions in bacteria

To investigate the dependence of the number of regulatory sites per intergenic region on genome size, we developed a new method for detecting purifying selection at noncoding positions in clades of related bacterial genomes. We comprehensively quantified evidence of purifying selection at noncoding...

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Autors principals: Molina, Nacho, van Nimwegen, Erik
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134783/
https://ncbi.nlm.nih.gov/pubmed/18032729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6759507
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