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Overexpression of Protein Kinase C β(II) Induces Colonic Hyperproliferation and Increased Sensitivity to Colon Carcinogenesis

Protein kinase C β(II) (PKC β(II)) has been implicated in proliferation of the intestinal epithelium. To investigate PKC β(II) function in vivo, we generated transgenic mice that overexpress PKC β(II) in the intestinal epithelium. Transgenic PKC β(II) mice exhibit hyperproliferation of the colonic e...

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Detaylı Bibliyografya
Asıl Yazarlar: Murray, Nicole R., Davidson, Laurie A., Chapkin, Robert S., Clay Gustafson, W., Schattenberg, Diane G., Fields, Alan P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133187/
https://ncbi.nlm.nih.gov/pubmed/10330400
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