Folate Transport Gene Inactivation in Mice Increases Sensitivity to Colon Carcinogenesis

Low dietary folate intake is associated with an increased risk for colon cancer; however, relevant genetic animal models are lacking. We therefore investigated the effect of targeted ablation of two folate transport genes, folate binding protein 1 (Folbp1) and reduced folate carrier 1 (RFC1), on fol...

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Detalhes bibliográficos
Main Authors: Ma, David W.L., Finnell, Richard H., Davidson, Laurie A., Callaway, Evelyn S., Spiegelstein, Ofer, Piedrahita, Jorge A., Salbaum, J. Michael, Kappen, Claudia, Weeks, Brad R., James, Jill, Bozinov, Daniel, Lupton, Joanne R., Chapkin, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938162/
https://ncbi.nlm.nih.gov/pubmed/15705887
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