The J-related Segment of Tim44 Is Essential for Cell Viability: A Mutant Tim44 Remains in the Mitochondrial Import Site, but Inefficiently Recruits mtHsp70 and Impairs Protein Translocation

Benzer Materyaller

• Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins.
  Yazar:: Voos, W, ve diğerleri
  Baskı/Yayın Bilgisi: (1996)
• The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44.
  Yazar:: Dekker, P J, ve diğerleri
  Baskı/Yayın Bilgisi: (1997)
• Mitochondrial Protein Import Motor: the ATPase Domain of Matrix Hsp70 Is Crucial for Binding to Tim44, while the Peptide Binding Domain and the Carboxy-Terminal Segment Play a Stimulatory Role
  Yazar:: Krimmer, Thomas, ve diğerleri
  Baskı/Yayın Bilgisi: (2000)
• Separation of structural and dynamic functions of the mitochondrial translocase: Tim44 is crucial for the inner membrane import sites in translocation of tightly folded domains, but not of loosely folded preproteins.
  Yazar:: Bömer, U, ve diğerleri
  Baskı/Yayın Bilgisi: (1998)
• The essential yeast protein MIM44 (encoded by MPI1) is involved in an early step of preprotein translocation across the mitochondrial inner membrane.
  Yazar:: Blom, J, ve diğerleri
  Baskı/Yayın Bilgisi: (1993)