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The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44.

Preprotein import into mitochondria is mediated by translocases located in the outer and inner membranes (Tom and Tim) and a matrix Hsp70-Tim44 driving system. By blue native electrophoresis, we identify an approximately 90K complex with assembled Tim23 and Tim17 as the core of the inner membrane im...

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Detalhes bibliográficos
Main Authors: Dekker, P J, Martin, F, Maarse, A C, Bömer, U, Müller, H, Guiard, B, Meijer, M, Rassow, J, Pfanner, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170172/
https://ncbi.nlm.nih.gov/pubmed/9312000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.17.5408
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