Separation of structural and dynamic functions of the mitochondrial translocase: Tim44 is crucial for the inner membrane import sites in translocation of tightly folded domains, but not of loosely folded preproteins.

Gelijkaardige items

• The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44.
  door: Dekker, P J, et al.
  Gepubliceerd in: (1997)
• The J-related Segment of Tim44 Is Essential for Cell Viability: A Mutant Tim44 Remains in the Mitochondrial Import Site, but Inefficiently Recruits mtHsp70 and Impairs Protein Translocation
  door: Merlin, Alessio, et al.
  Gepubliceerd in: (1999)
• Mitochondrial Import Driving Forces: Enhanced Trapping by Matrix Hsp70 Stimulates Translocation and Reduces the Membrane Potential Dependence of Loosely Folded Preproteins
  door: Geissler, Andreas, et al.
  Gepubliceerd in: (2001)
• Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins.
  door: Voos, W, et al.
  Gepubliceerd in: (1996)
• Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane.
  door: Bömer, U, et al.
  Gepubliceerd in: (1997)