Separation of structural and dynamic functions of the mitochondrial translocase: Tim44 is crucial for the inner membrane import sites in translocation of tightly folded domains, but not of loosely folded preproteins.

The essential gene TIM44 encodes a subunit of the inner mitochondrial membrane preprotein translocase that forms a complex with the matrix heat-shock protein Hsp70. The specific role of Tim44 in protein import has not yet been defined because of the lack of means to block its function. Here we repor...

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Main Authors: Bömer, U, Maarse, A C, Martin, F, Geissler, A, Merlin, A, Schönfisch, B, Meijer, M, Pfanner, N, Rassow, J
Formato: Artigo
Idioma:Inglês
Publicado: 1998
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170756/
https://ncbi.nlm.nih.gov/pubmed/9687491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.15.4226
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