Molecular Dissection of the Rho-associated Protein Kinase (p160ROCK)-regulated Neurite Remodeling in Neuroblastoma N1E-115 Cells

A critical role for the small GTPase Rho and one of its targets, p160ROCK (a Rho-associated coiled coil-forming protein kinase), in neurite remodeling was examined in neuroblastoma N1E-115 cells. Using wild-type and a dominant-negative form of p160ROCK and a p160ROCK-specific inhibitor, Y-27632, we...

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Main Authors: Hirose, Masaya, Ishizaki, Toshimasa, Watanabe, Naoki, Uehata, Masayoshi, Kranenburg, Onno, Moolenaar, Wouter H., Matsumura, Fumio, Maekawa, Midori, Bito, Haruhiko, Narumiya, Shuh
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133015/
https://ncbi.nlm.nih.gov/pubmed/9647654
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