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Integrin-dependent translocation of p160ROCK to cytoskeletal complex in thrombin-stimulated human platelets.

p160(ROCK) is a protein serine/threonine kinase that binds to GTP-Rho and is activated by this binding. We have recently found that the expression of p160(ROCK) induces focal adhesions and stress fibres in HeLa cells, whereas a dominant-negative form of this kinase suppresses Rho-induced formation o...

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Bibliographic Details
Main Authors: Fujita, A, Saito, Y, Ishizaki, T, Maekawa, M, Fujisawa, K, Ushikubi, F, Narumiya, S
Format: Artigo
Language:Inglês
Published: 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218985/
https://ncbi.nlm.nih.gov/pubmed/9396719
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