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Recruitment and the Role of Nuclear Localization in Polyglutamine-mediated Aggregation

The inherited neurodegenerative diseases caused by an expanded glutamine repeat share the pathologic feature of intranuclear aggregates or inclusions (NI). Here in cell-based studies of the spinocerebellar ataxia type-3 disease protein, ataxin-3, we address two issues central to aggregation: the rol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Perez, Matthew K., Paulson, Henry L., Pendse, Sagun J., Saionz, Sarah J., Bonini, Nancy M., Pittman, Randall N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132986/
https://ncbi.nlm.nih.gov/pubmed/9852144
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