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Analysis of the Role of Heat Shock Protein (Hsp) Molecular Chaperones in Polyglutamine Disease

Polyglutamine (polygln) diseases are a group of inherited neurodegenerative disorders characterized by protein misfolding and aggregation. Here, we investigate the role in polygln disease of heat shock proteins (Hsps), the major class of molecular chaperones responsible for modulating protein foldin...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Chai, Yaohui, Koppenhafer, Stacia L., Bonini, Nancy M., Paulson, Henry L.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782415/
https://ncbi.nlm.nih.gov/pubmed/10575031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-23-10338.1999
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