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Analysis of the Role of Heat Shock Protein (Hsp) Molecular Chaperones in Polyglutamine Disease

Polyglutamine (polygln) diseases are a group of inherited neurodegenerative disorders characterized by protein misfolding and aggregation. Here, we investigate the role in polygln disease of heat shock proteins (Hsps), the major class of molecular chaperones responsible for modulating protein foldin...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Chai, Yaohui, Koppenhafer, Stacia L., Bonini, Nancy M., Paulson, Henry L.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782415/
https://ncbi.nlm.nih.gov/pubmed/10575031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-23-10338.1999
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