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Analysis of the Role of Heat Shock Protein (Hsp) Molecular Chaperones in Polyglutamine Disease

Polyglutamine (polygln) diseases are a group of inherited neurodegenerative disorders characterized by protein misfolding and aggregation. Here, we investigate the role in polygln disease of heat shock proteins (Hsps), the major class of molecular chaperones responsible for modulating protein foldin...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Chai, Yaohui, Koppenhafer, Stacia L., Bonini, Nancy M., Paulson, Henry L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782415/
https://ncbi.nlm.nih.gov/pubmed/10575031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-23-10338.1999
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