Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3

Accumulation of mutant polyglutamine proteins in intraneuronal inclusions is a hallmark of polyglutamine diseases. Impairment of protein clearance systems and sequestration of clearance-related proteins into inclusions occur in many protein folding diseases, including the polyglutamine diseases. The...

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Publicado en:Neurobiol Dis
Main Authors: Zeng, Li, Wang, Bo, Merillat, Sean A, Minakawa, Eiko, Perkins, Matthew D, Ramani, Biswarathan, Tallaksen-Greene, Sara J., do Carmo Costa, Maria, Albin, Roger L., Paulson, Henry L.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642276/
https://ncbi.nlm.nih.gov/pubmed/26141599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.06.017
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