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Analysis Of Rev1p And Pol ζ In Mitochondrial Mutagenesis Suggests An Alternative Pathway Of Damage Tolerance
Ultraviolet light is a potent DNA damaging agent that induces bulky lesions in DNA which block the replicative polymerases. In order to ensure continued DNA replication and cell viability, specialized translesion polymerases bypass these lesions at the expense of introducing mutations in the nascent...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2129123/ https://ncbi.nlm.nih.gov/pubmed/17689152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.06.005 |
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