A carregar...

Roles for the Rad27 Flap Endonuclease in Mitochondrial Mutagenesis and Double-Strand Break Repair in Saccharomyces cerevisiae

The structure-specific nuclease, Rad27p/FEN1, plays a crucial role in DNA repair and replication mechanisms in the nucleus. Genetic assays using the rad27-∆ mutant have shown altered rates of DNA recombination, microsatellite instability, and point mutation in mitochondria. In this study, we examine...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Nagarajan, Prabha, Prevost, Christopher T., Stein, Alexis, Kasimer, Rachel, Kalifa, Lidza, Sia, Elaine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499190/
https://ncbi.nlm.nih.gov/pubmed/28450457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.195149
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!