Llwytho...

Roles for the Rad27 Flap Endonuclease in Mitochondrial Mutagenesis and Double-Strand Break Repair in Saccharomyces cerevisiae

The structure-specific nuclease, Rad27p/FEN1, plays a crucial role in DNA repair and replication mechanisms in the nucleus. Genetic assays using the rad27-∆ mutant have shown altered rates of DNA recombination, microsatellite instability, and point mutation in mitochondria. In this study, we examine...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genetics
Prif Awduron: Nagarajan, Prabha, Prevost, Christopher T., Stein, Alexis, Kasimer, Rachel, Kalifa, Lidza, Sia, Elaine A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Genetics Society of America 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499190/
https://ncbi.nlm.nih.gov/pubmed/28450457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.195149
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