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Regioselective double Suzuki couplings of 4,5-dibromothiophene-2-carboxaldehyde

Conditions have been identified that enable the one-pot double Suzuki coupling of 4,5-dibromothiophene-2-carboxaldehyde to proceed in good yield. The key to success in these reactions is the use of minimal amounts of water to avoid significant amounts of dehalogenation during the first coupling.

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Hlavní autoři: Handy, Scott T., Mayi, Diyar
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128684/
https://ncbi.nlm.nih.gov/pubmed/19008934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2007.09.114
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