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Regioselective double Suzuki couplings of 4,5-dibromothiophene-2-carboxaldehyde

Conditions have been identified that enable the one-pot double Suzuki coupling of 4,5-dibromothiophene-2-carboxaldehyde to proceed in good yield. The key to success in these reactions is the use of minimal amounts of water to avoid significant amounts of dehalogenation during the first coupling.

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Dettagli Bibliografici
Autori principali: Handy, Scott T., Mayi, Diyar
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128684/
https://ncbi.nlm.nih.gov/pubmed/19008934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2007.09.114
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