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One-pot Double Suzuki Couplings of Dichloropyrimidines

An effective one-pot, regioselective double Suzuki coupling of 2,4-dichloropyrimidine has been developed, which enables the quick and efficient synthesis of diarylated pyrimidines. The choice of solvent proved critical to the success of this reaction sequence, with alcoholic solvent mixtures affordi...

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Detalhes bibliográficos
Main Authors: Anderson, Samantha C., Handy, Scott T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285113/
https://ncbi.nlm.nih.gov/pubmed/22368305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0030-1258150
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