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Regioselective double Suzuki couplings of 4,5-dibromothiophene-2-carboxaldehyde

Conditions have been identified that enable the one-pot double Suzuki coupling of 4,5-dibromothiophene-2-carboxaldehyde to proceed in good yield. The key to success in these reactions is the use of minimal amounts of water to avoid significant amounts of dehalogenation during the first coupling.

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Detalhes bibliográficos
Main Authors: Handy, Scott T., Mayi, Diyar
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128684/
https://ncbi.nlm.nih.gov/pubmed/19008934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2007.09.114
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