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Regioselective double Suzuki couplings of 4,5-dibromothiophene-2-carboxaldehyde

Conditions have been identified that enable the one-pot double Suzuki coupling of 4,5-dibromothiophene-2-carboxaldehyde to proceed in good yield. The key to success in these reactions is the use of minimal amounts of water to avoid significant amounts of dehalogenation during the first coupling.

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Bibliografiske detaljer
Main Authors: Handy, Scott T., Mayi, Diyar
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128684/
https://ncbi.nlm.nih.gov/pubmed/19008934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2007.09.114
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