SCF(β-TrCP) ubiquitin ligase-mediated processing of NF-κB p105 requires phosphorylation of its C-terminus by IκB kinase

Processing of the p105 precursor to form the active subunit p50 of the NF-κB transcription factor is a unique case in which the ubiquitin system is involved in limited processing rather than in complete destruction of the target substrate. A glycine-rich region along with a downstream acidic domain...

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Dades bibliogràfiques

Publicat a:	EMBO J
Autors principals:	Orian, Amir, Gonen, Hedva, Bercovich, Beatrice, Fajerman, Ifat, Eytan, Esther, Israël, Alain, Mercurio, Frank, Iwai, Kazuhiro, Schwartz, Alan L., Ciechanover, Aaron
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Publishing Group 2000
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10835356/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.11.2580
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