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Origins of minigene-dependent growth inhibition in bacterial cells

The expression of very short open reading frames in Escherichia coli can lead to the inhibition of translation and an arrest in cell growth. Inhibition occurs because peptidyl-tRNA hydrolase fails to recycle sufficiently rapidly peptidyl-tRNA released from ribosomes at the stop signal in competition...

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Bibliografske podrobnosti
Main Authors: Heurgué-Hamard, Valérie, Dinçbas, Vildan, Buckingham, Richard H., Ehrenberg, Måns
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC212743/
https://ncbi.nlm.nih.gov/pubmed/10835367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.11.2701
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