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Origins of minigene-dependent growth inhibition in bacterial cells

The expression of very short open reading frames in Escherichia coli can lead to the inhibition of translation and an arrest in cell growth. Inhibition occurs because peptidyl-tRNA hydrolase fails to recycle sufficiently rapidly peptidyl-tRNA released from ribosomes at the stop signal in competition...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Heurgué-Hamard, Valérie, Dinçbas, Vildan, Buckingham, Richard H., Ehrenberg, Måns
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10835367/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.11.2701
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