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Origins of minigene-dependent growth inhibition in bacterial cells

The expression of very short open reading frames in Escherichia coli can lead to the inhibition of translation and an arrest in cell growth. Inhibition occurs because peptidyl-tRNA hydrolase fails to recycle sufficiently rapidly peptidyl-tRNA released from ribosomes at the stop signal in competition...

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Detalhes bibliográficos
Main Authors: Heurgué-Hamard, Valérie, Dinçbas, Vildan, Buckingham, Richard H., Ehrenberg, Måns
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC212743/
https://ncbi.nlm.nih.gov/pubmed/10835367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.11.2701
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