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Mammalian HEMK1 methylates glutamine residue of the GGQ motif of mitochondrial release factors

Abstract Despite limited reports on glutamine methylation, methylated glutamine is found to be highly conserved in a "GGQ" motif in both prokaryotes and eukaryotes. In bacteria, glutamine methylation of peptide chain release factors 1/2 (RF1/2) by the enzyme PrmC is essential for translational termi...

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Principais autores: Qi Fang, Yusuke Kimura, Tadahiro Shimazu, Takehiro Suzuki, Ayumi Yamada, Naoshi Dohmae, Shintaro Iwasaki, Yoichi Shinkai
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2022-03-01
סדרה:Scientific Reports
גישה מקוונת:https://doi.org/10.1038/s41598-022-08061-y
תגים: הוספת תג
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