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Origins of minigene-dependent growth inhibition in bacterial cells

The expression of very short open reading frames in Escherichia coli can lead to the inhibition of translation and an arrest in cell growth. Inhibition occurs because peptidyl-tRNA hydrolase fails to recycle sufficiently rapidly peptidyl-tRNA released from ribosomes at the stop signal in competition...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Heurgué-Hamard, Valérie, Dinçbas, Vildan, Buckingham, Richard H., Ehrenberg, Måns
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10835367/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.11.2701
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