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Regulation of mature T lymphocyte proliferation and differentiation by Par-4
The genetic inactivation of the atypical protein kinase C (aPKC) inhibitor, Par-4, gives rise to increased NF-κB activation and decreased stimulation of JNK in embryo fibroblasts. Here we have characterized the immunological phenotype of the Par-4(–/–) mice and found that the loss of this gene leads...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC212727/ https://ncbi.nlm.nih.gov/pubmed/12970181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg460 |
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