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Regulation of mature T lymphocyte proliferation and differentiation by Par-4

The genetic inactivation of the atypical protein kinase C (aPKC) inhibitor, Par-4, gives rise to increased NF-κB activation and decreased stimulation of JNK in embryo fibroblasts. Here we have characterized the immunological phenotype of the Par-4(–/–) mice and found that the loss of this gene leads...

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Bibliografiske detaljer
Main Authors: Lafuente, María José, Martin, Pilar, Garcia-Cao, Isabel, Diaz-Meco, María Teresa, Serrano, Manuel, Moscat, Jorge
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC212727/
https://ncbi.nlm.nih.gov/pubmed/12970181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg460
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