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Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis

Mnt is a Max-interacting transcriptional repressor that has been hypothesized to function as a Myc antagonist. To investigate Mnt function we deleted the Mnt gene in mice. Since mice lacking Mnt were born severely runted and typically died within several days of birth, mouse embryo fibroblasts (MEFs...

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Bibliografiske detaljer
Main Authors: Hurlin, Peter J., Zhou, Zi-Qiang, Toyo-oka, Kazuhito, Ota, Sara, Walker, William L., Hirotsune, Shinji, Wynshaw-Boris, Anthony
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC212711/
https://ncbi.nlm.nih.gov/pubmed/12970171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg442
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