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Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis
Mnt is a Max-interacting transcriptional repressor that has been hypothesized to function as a Myc antagonist. To investigate Mnt function we deleted the Mnt gene in mice. Since mice lacking Mnt were born severely runted and typically died within several days of birth, mouse embryo fibroblasts (MEFs...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC212711/ https://ncbi.nlm.nih.gov/pubmed/12970171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg442 |
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