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Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis

Mnt is a Max-interacting transcriptional repressor that has been hypothesized to function as a Myc antagonist. To investigate Mnt function we deleted the Mnt gene in mice. Since mice lacking Mnt were born severely runted and typically died within several days of birth, mouse embryo fibroblasts (MEFs...

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Autors principals: Hurlin, Peter J., Zhou, Zi-Qiang, Toyo-oka, Kazuhito, Ota, Sara, Walker, William L., Hirotsune, Shinji, Wynshaw-Boris, Anthony
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC212711/
https://ncbi.nlm.nih.gov/pubmed/12970171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg442
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