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Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis

Mnt is a Max-interacting transcriptional repressor that has been hypothesized to function as a Myc antagonist. To investigate Mnt function we deleted the Mnt gene in mice. Since mice lacking Mnt were born severely runted and typically died within several days of birth, mouse embryo fibroblasts (MEFs...

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Bibliografische gegevens
Hoofdauteurs: Hurlin, Peter J., Zhou, Zi-Qiang, Toyo-oka, Kazuhito, Ota, Sara, Walker, William L., Hirotsune, Shinji, Wynshaw-Boris, Anthony
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC212711/
https://ncbi.nlm.nih.gov/pubmed/12970171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg442
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