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Inflammatory Disease and Lymphomagenesis Caused by Deletion of the Myc Antagonist Mnt in T Cells

Mnt is a Max-interacting protein that can antagonize the activities of Myc oncoproteins in cultured cells. Mnt null mice die soon after birth, but conditional deletion of Mnt in breast epithelium leads to tumor formation. These and related data suggest that Mnt functions as a tumor suppressor. Here...

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Hlavní autoři: Dezfouli, Shala, Bakke, Antony, Huang, Jie, Wynshaw-Boris, Anthony, Hurlin, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430277/
https://ncbi.nlm.nih.gov/pubmed/16507988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.6.2080-2092.2006
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