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Inflammatory Disease and Lymphomagenesis Caused by Deletion of the Myc Antagonist Mnt in T Cells

Mnt is a Max-interacting protein that can antagonize the activities of Myc oncoproteins in cultured cells. Mnt null mice die soon after birth, but conditional deletion of Mnt in breast epithelium leads to tumor formation. These and related data suggest that Mnt functions as a tumor suppressor. Here...

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Detalhes bibliográficos
Main Authors: Dezfouli, Shala, Bakke, Antony, Huang, Jie, Wynshaw-Boris, Anthony, Hurlin, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430277/
https://ncbi.nlm.nih.gov/pubmed/16507988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.6.2080-2092.2006
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