Ligand binding was acquired during evolution of nuclear receptors

The nuclear receptor (NR) superfamily comprises, in addition to ligand-activated transcription factors, members for which no ligand has been identified to date. We demonstrate that orphan receptors are randomly distributed in the evolutionary tree and that there is no relationship between the positi...

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Detalhes bibliográficos
Main Authors: Escriva, Hector, Safi, Rachid, Hänni, Catherine, Langlois, Marie-Claire, Saumitou-Laprade, Pierre, Stehelin, Dominique, Capron, André, Pierce, Raymond, Laudet, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21239/
https://ncbi.nlm.nih.gov/pubmed/9192646
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