Ligand binding was acquired during evolution of nuclear receptors

The nuclear receptor (NR) superfamily comprises, in addition to ligand-activated transcription factors, members for which no ligand has been identified to date. We demonstrate that orphan receptors are randomly distributed in the evolutionary tree and that there is no relationship between the positi...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Escriva, Hector, Safi, Rachid, Hänni, Catherine, Langlois, Marie-Claire, Saumitou-Laprade, Pierre, Stehelin, Dominique, Capron, André, Pierce, Raymond, Laudet, Vincent
التنسيق: Artigo
اللغة:Inglês
منشور في: The National Academy of Sciences of the USA 1997
الموضوعات:
Biological Sciences
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC21239/
https://ncbi.nlm.nih.gov/pubmed/9192646
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