Ligand binding was acquired during evolution of nuclear receptors

The nuclear receptor (NR) superfamily comprises, in addition to ligand-activated transcription factors, members for which no ligand has been identified to date. We demonstrate that orphan receptors are randomly distributed in the evolutionary tree and that there is no relationship between the positi...

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Detaylı Bibliyografya
Asıl Yazarlar: Escriva, Hector, Safi, Rachid, Hänni, Catherine, Langlois, Marie-Claire, Saumitou-Laprade, Pierre, Stehelin, Dominique, Capron, André, Pierce, Raymond, Laudet, Vincent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences of the USA 1997
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC21239/
https://ncbi.nlm.nih.gov/pubmed/9192646
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