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Overexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosome
BACKGROUND: Previously we cloned the human MNB/DYRK1A gene from the "Down syndrome critical region" on chromosome 21. This gene encodes a dual specificity protein kinase that catalyzes its autophosphorylation on serine/threonine and tyrosine residues. But, the functions of the MNB/DYRK1A g...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC212362/ https://ncbi.nlm.nih.gov/pubmed/12964950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-4-12 |
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