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Disruption of clathrin-mediated trafficking causes centrosome overduplication and senescence
The Hsc70 cochaperone, G cyclin-associated kinase (GAK), has been shown to be essential for the chaperoning of clathrin by Hsc70 in the cell. In this study, we used conditional GAK knockout mouse embryonic fibroblasts (MEFs) to determine the effect of completely inhibiting clathrin-dependent traffic...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3868896/ https://ncbi.nlm.nih.gov/pubmed/24138026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12132 |
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