Llwytho...

Disruption of clathrin-mediated trafficking causes centrosome overduplication and senescence

The Hsc70 cochaperone, G cyclin-associated kinase (GAK), has been shown to be essential for the chaperoning of clathrin by Hsc70 in the cell. In this study, we used conditional GAK knockout mouse embryonic fibroblasts (MEFs) to determine the effect of completely inhibiting clathrin-dependent traffic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Olszewski, Maciej B., Chandris, Panagiotis, Park, Bum-Chan, Eisenberg, Evan, Greene, Lois E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868896/
https://ncbi.nlm.nih.gov/pubmed/24138026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12132
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