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The p53-inhibitor Pifithrin-α inhibits Firefly Luciferase activity in vivo and in vitro

BACKGROUND: Pifithrin-α is a small molecule inhibitor of p53 transcriptional activity. It has been proposed that the use of pifithrin-α in conjunction with chemotherapeutic and radiation therapies for cancer will reduce the side effects of these treatments in normal tissue that still contains wild t...

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Detalhes bibliográficos
Main Authors: Rocha, Sonia, Campbell, Kirsteen J, Roche, Kevin C, Perkins, Neil D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC212280/
https://ncbi.nlm.nih.gov/pubmed/12967348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-4-9
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