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Inhibition of Firefly Luciferase by General Anesthetics: Effect on In Vitro and In Vivo Bioluminescence Imaging

Bioluminescence imaging is routinely performed in anesthetized mice. Often isoflurane anesthesia is used because of its ease of use and fast induction/recovery. However, general anesthetics have been described as important inhibitors of the luciferase enzyme reaction. AIM: To investigate frequently...

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Detalhes bibliográficos
Main Authors: Keyaerts, Marleen, Remory, Isabel, Caveliers, Vicky, Breckpot, Karine, Bos, Tomas J., Poelaert, Jan, Bossuyt, Axel, Lahoutte, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254645/
https://ncbi.nlm.nih.gov/pubmed/22253879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030061
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