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β‐Deuterium Isotope Effects on Firefly Luciferase Bioluminescence

A 5,5‐d(2)‐luciferin was prepared to measure isotope effects on reactions of two intermediates in firefly bioluminescence: emission by oxyluciferin and elimination of a putative luciferyl adenylate hydroperoxide to dehydroluciferin. A negligible isotope effect on bioluminescence provides further sup...

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Detalhes bibliográficos
Publicado no:ChemistryOpen
Main Authors: Pirrung, Michael C., Dorsey, Allyson, Howitt, Natalie De, Liao, Jiayu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715289/
https://ncbi.nlm.nih.gov/pubmed/29226056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201700136
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